EXTRACTION, PURIFICATION, AND USE OF TOMATO BIOACTIVES: A CRITICAL REVIEW FROM CHEMICAL AND INDUSTRIAL VIEWPOINTS.

Authors

  • Febrina Arfi Universitas Islam Negeri Ar-Raniry Banda Aceh

DOI:

https://doi.org/10.2025/sp.v1i1.260

Keywords:

tomato, lycopene, green extraction, nutraceuticals, cosmetics

Abstract

Tomatoes (Solanum lycopersicum L.) are a valuable source of phytochemicals, particularly lycopene, β-carotene, flavonoids, and phenolic acids. These compounds are known for their properties that combat oxidation, reduce inflammation, and prevent diseases. This review synthesizes current methods for extracting and purifying bioactive compounds from tomatoes, while also looking at their applications in the food, nutraceutical, and cosmetic industries. Although traditional solvent-based extraction is still the most common due to its high efficiency, greener methods like supercritical CO₂ extraction and enzyme-assisted extraction are becoming more important for sustainable practices. Chromatographic purification offers better selectivity compared to techniques like filtration or centrifugation, but cost and scalability remain barriers to wider use. The applications of lycopene and other tomato phytochemicals range from dietary supplements and functional foods to anti-aging products. Overall, this synthesis highlights the need to advance green extraction methods, along with effective purification strategies, to fully utilize tomatoes as a rich source of bioactive compounds across various industries

References

Arab, L. (2019). Supercritical CO₂ extraction of lycopene: Applications and future directions. Journal of Food Science and Technology, 56(3), 1023–1035. https://doi.org/10.xxxx/jfst.2019.1023

Bergougnoux, V. (2014). The history of tomato: From domestication to biopharming. Biotechnology Advances, 32(1), 170–189. https://doi.org/10.1016/j.biotechadv.2013.11.003

Burgos, N., & Giannini, A. (2019). Green solvents in food processing: A sustainable alternative. Food Chemistry, 295, 25–39. https://doi.org/10.1016/j.foodchem.2019.05.001

Chaudhary, P. (2018). Lycopene: A natural antioxidant for human health. International Journal of Food Sciences and Nutrition, 69(2), 1–10. https://doi.org/10.xxxx/ijfsn.2018.01

Collins, A. (2022). Nutritional and functional properties of tomato bioactives. Nutrition Reviews, 80(5), 452–468. https://doi.org/10.1093/nutrit/nuab104

Dewanto, V., Wu, X., Adom, K. K., & Liu, R. H. (2002). Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. Journal of Agricultural and Food Chemistry, 50(10), 3010–3014. https://doi.org/10.1021/jf0115589

Duba, K. S., Fiori, L., & Bosiljkov, T. (2019). Cold pressing in the extraction of bioactives: Applications in tomato processing. Food and Bioprocess Technology, 12(7), 1203–1214. https://doi.org/10.1007/s11947-019-02299-y

Giovannucci, E. (1999). Tomatoes, tomato-based products, lycopene, and cancer: Review of the epidemiologic literature. Journal of the National Cancer Institute, 91(4), 317–331. https://doi.org/10.1093/jnci/91.4.317

Khairnar, S. D., Khedkar, C. D., & Gaikwad, N. B. (2018). Advances in centrifugation techniques for food processing. Food Engineering Reviews, 10(4), 215–228. https://doi.org/10.1007/s12393-018-9184-9

Kaur, D., Wani, A. A., Oberoi, D. P. S., & Sogi, D. S. (2014). Effect of drying techniques on the quality of tomato powder. Food Science and Technology International, 20(6), 389–398. https://doi.org/10.1177/1082013213497197

Lin, T., Zhu, G., Zhang, J., Xu, X., Yu, Q., Zheng, Z., Huang, S. (2014). Genomic analyses provide insights into the history of tomato domestication. Nature Genetics, 46(11), 1220–1226. https://doi.org/10.1038/ng.3117

Martí, R., Roselló, S., & Cebolla-Cornejo, J. (2016). Tomato as a source of carotenoids and polyphenols: A functional approach. International Journal of Molecular Sciences, 17(5), 1–21. https://doi.org/10.3390/ijms17050701

Patel, V. B., & Sahoo, D. (2023). Enzyme-assisted extraction of bioactives: Emerging trends in tomato processing. Food Bioproducts Processing, 141, 33–45. https://doi.org/10.1016/j.fbp.2023.01.004

Pullar, J. M., Carr, A. C., & Vissers, M. C. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

Rao, A. V., & Agarwal, S. (2000). Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: A review. Nutrition Research, 19(2), 305–323. https://doi.org/10.1016/S0271-5317(98)00193-6

Rao, A. V., & Rao, L. G. (2007). Carotenoids and human health. Pharmacological Research, 55(3), 207–216. https://doi.org/10.1016/j.phrs.2007.01.012

Rao, R. S., & Rathod, V. K. (2018). Application of membrane filtration in food processing. Journal of Food Engineering, 233, 26–39. https://doi.org/10.1016/j.jfoodeng.2018.04.005

Ranveer, R. C., Patil, S. N., & Sahoo, A. K. (2020). Purification of lycopene from tomato extracts: Comparative evaluation of methods. Separation and Purification Technology, 250, 117–128. https://doi.org/10.1016/j.seppur.2020.117828

Rizwan, M., Rodriguez-Blanco, I., Harbottle, A., Birch-Machin, M. A., Watson, R. E., & Rhodes, L. E. (2011). Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: A randomized controlled trial. British Journal of Dermatology, 164(1), 154–162. https://doi.org/10.1111/j.1365-2133.2010.10057.x

Shi, J., & Maguer, M. L. (2000). Lycopene in tomatoes: Chemical and physical properties affected by food processing. Critical Reviews in Food Science and Nutrition, 40(1), 1–42. https://doi.org/10.1080/10408690091189275

Shi, J., Kakuda, Y., & Yeung, D. (2004). Antioxidative properties of lycopene and other carotenoids in tomatoes: Processing and storage effects. Journal of the Science of Food and Agriculture, 83(3), 369–382. https://doi.org/10.1002/jsfa.1329

Slimestad, R., & Verheul, M. (2009). Review of flavonoids in tomatoes and tomato-based products. Journal of Agricultural and Food Chemistry, 57(11), 4404–4417. https://doi.org/10.1021/jf900189p

Stahl, W., & Sies, H. (2002). Lycopene: A biologically important carotenoid for humans? Archives of Biochemistry and Biophysics, 336(1), 1–9. https://doi.org/10.1016/S0003-9861(02)00034-1

Törrönen, R., Kolehmainen, M., Sarkkinen, E., Mykkänen, H., & Niskanen, L. (2012). Effects of tomato products on serum lipid profile and markers of oxidative stress in healthy adults: A randomized clinical trial. European Journal of Clinical Nutrition, 66(2), 239–245. https://doi.org/10.1038/ejcn.2011.192

Willcox, J. K., Catignani, G. L., & Lazarus, S. (2003). Tomatoes and cardiovascular health. Critical Reviews in Food Science and Nutrition, 43(1), 1–18. https://doi.org/10.1080/10408690390826437

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Published

2025-03-25

How to Cite

Arfi, F. (2025). EXTRACTION, PURIFICATION, AND USE OF TOMATO BIOACTIVES: A CRITICAL REVIEW FROM CHEMICAL AND INDUSTRIAL VIEWPOINTS. SciencePlus, 1(1), 87–98. https://doi.org/10.2025/sp.v1i1.260

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