EXTRACTION, PURIFICATION, AND USE OF TOMATO BIOACTIVES: A CRITICAL REVIEW FROM CHEMICAL AND INDUSTRIAL VIEWPOINTS.
DOI:
https://doi.org/10.2025/sp.v1i1.260Keywords:
tomato, lycopene, green extraction, nutraceuticals, cosmeticsAbstract
Tomatoes (Solanum lycopersicum L.) are a valuable source of phytochemicals, particularly lycopene, β-carotene, flavonoids, and phenolic acids. These compounds are known for their properties that combat oxidation, reduce inflammation, and prevent diseases. This review synthesizes current methods for extracting and purifying bioactive compounds from tomatoes, while also looking at their applications in the food, nutraceutical, and cosmetic industries. Although traditional solvent-based extraction is still the most common due to its high efficiency, greener methods like supercritical CO₂ extraction and enzyme-assisted extraction are becoming more important for sustainable practices. Chromatographic purification offers better selectivity compared to techniques like filtration or centrifugation, but cost and scalability remain barriers to wider use. The applications of lycopene and other tomato phytochemicals range from dietary supplements and functional foods to anti-aging products. Overall, this synthesis highlights the need to advance green extraction methods, along with effective purification strategies, to fully utilize tomatoes as a rich source of bioactive compounds across various industries
References
Arab, L. (2019). Supercritical CO₂ extraction of lycopene: Applications and future directions. Journal of Food Science and Technology, 56(3), 1023–1035. https://doi.org/10.xxxx/jfst.2019.1023
Bergougnoux, V. (2014). The history of tomato: From domestication to biopharming. Biotechnology Advances, 32(1), 170–189. https://doi.org/10.1016/j.biotechadv.2013.11.003
Burgos, N., & Giannini, A. (2019). Green solvents in food processing: A sustainable alternative. Food Chemistry, 295, 25–39. https://doi.org/10.1016/j.foodchem.2019.05.001
Chaudhary, P. (2018). Lycopene: A natural antioxidant for human health. International Journal of Food Sciences and Nutrition, 69(2), 1–10. https://doi.org/10.xxxx/ijfsn.2018.01
Collins, A. (2022). Nutritional and functional properties of tomato bioactives. Nutrition Reviews, 80(5), 452–468. https://doi.org/10.1093/nutrit/nuab104
Dewanto, V., Wu, X., Adom, K. K., & Liu, R. H. (2002). Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. Journal of Agricultural and Food Chemistry, 50(10), 3010–3014. https://doi.org/10.1021/jf0115589
Duba, K. S., Fiori, L., & Bosiljkov, T. (2019). Cold pressing in the extraction of bioactives: Applications in tomato processing. Food and Bioprocess Technology, 12(7), 1203–1214. https://doi.org/10.1007/s11947-019-02299-y
Giovannucci, E. (1999). Tomatoes, tomato-based products, lycopene, and cancer: Review of the epidemiologic literature. Journal of the National Cancer Institute, 91(4), 317–331. https://doi.org/10.1093/jnci/91.4.317
Khairnar, S. D., Khedkar, C. D., & Gaikwad, N. B. (2018). Advances in centrifugation techniques for food processing. Food Engineering Reviews, 10(4), 215–228. https://doi.org/10.1007/s12393-018-9184-9
Kaur, D., Wani, A. A., Oberoi, D. P. S., & Sogi, D. S. (2014). Effect of drying techniques on the quality of tomato powder. Food Science and Technology International, 20(6), 389–398. https://doi.org/10.1177/1082013213497197
Lin, T., Zhu, G., Zhang, J., Xu, X., Yu, Q., Zheng, Z., Huang, S. (2014). Genomic analyses provide insights into the history of tomato domestication. Nature Genetics, 46(11), 1220–1226. https://doi.org/10.1038/ng.3117
Martí, R., Roselló, S., & Cebolla-Cornejo, J. (2016). Tomato as a source of carotenoids and polyphenols: A functional approach. International Journal of Molecular Sciences, 17(5), 1–21. https://doi.org/10.3390/ijms17050701
Patel, V. B., & Sahoo, D. (2023). Enzyme-assisted extraction of bioactives: Emerging trends in tomato processing. Food Bioproducts Processing, 141, 33–45. https://doi.org/10.1016/j.fbp.2023.01.004
Pullar, J. M., Carr, A. C., & Vissers, M. C. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866
Rao, A. V., & Agarwal, S. (2000). Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: A review. Nutrition Research, 19(2), 305–323. https://doi.org/10.1016/S0271-5317(98)00193-6
Rao, A. V., & Rao, L. G. (2007). Carotenoids and human health. Pharmacological Research, 55(3), 207–216. https://doi.org/10.1016/j.phrs.2007.01.012
Rao, R. S., & Rathod, V. K. (2018). Application of membrane filtration in food processing. Journal of Food Engineering, 233, 26–39. https://doi.org/10.1016/j.jfoodeng.2018.04.005
Ranveer, R. C., Patil, S. N., & Sahoo, A. K. (2020). Purification of lycopene from tomato extracts: Comparative evaluation of methods. Separation and Purification Technology, 250, 117–128. https://doi.org/10.1016/j.seppur.2020.117828
Rizwan, M., Rodriguez-Blanco, I., Harbottle, A., Birch-Machin, M. A., Watson, R. E., & Rhodes, L. E. (2011). Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: A randomized controlled trial. British Journal of Dermatology, 164(1), 154–162. https://doi.org/10.1111/j.1365-2133.2010.10057.x
Shi, J., & Maguer, M. L. (2000). Lycopene in tomatoes: Chemical and physical properties affected by food processing. Critical Reviews in Food Science and Nutrition, 40(1), 1–42. https://doi.org/10.1080/10408690091189275
Shi, J., Kakuda, Y., & Yeung, D. (2004). Antioxidative properties of lycopene and other carotenoids in tomatoes: Processing and storage effects. Journal of the Science of Food and Agriculture, 83(3), 369–382. https://doi.org/10.1002/jsfa.1329
Slimestad, R., & Verheul, M. (2009). Review of flavonoids in tomatoes and tomato-based products. Journal of Agricultural and Food Chemistry, 57(11), 4404–4417. https://doi.org/10.1021/jf900189p
Stahl, W., & Sies, H. (2002). Lycopene: A biologically important carotenoid for humans? Archives of Biochemistry and Biophysics, 336(1), 1–9. https://doi.org/10.1016/S0003-9861(02)00034-1
Törrönen, R., Kolehmainen, M., Sarkkinen, E., Mykkänen, H., & Niskanen, L. (2012). Effects of tomato products on serum lipid profile and markers of oxidative stress in healthy adults: A randomized clinical trial. European Journal of Clinical Nutrition, 66(2), 239–245. https://doi.org/10.1038/ejcn.2011.192
Willcox, J. K., Catignani, G. L., & Lazarus, S. (2003). Tomatoes and cardiovascular health. Critical Reviews in Food Science and Nutrition, 43(1), 1–18. https://doi.org/10.1080/10408690390826437
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